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The Mouse Nervous System || Mouse Models of Mental Illness and Neurological Disease

โœ Scribed by Hickey, Miriam

Book ID
121194732
Publisher
Elsevier
Year
2012
Tongue
English
Weight
307 KB
Edition
1
Category
Article
ISBN
0123694973

No coin nor oath required. For personal study only.

โœฆ Synopsis

The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience.

  • Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases
  • A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states
  • A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area
  • Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases
  • Examples of the use of mouse models in the study of neurological illness

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Knock-out mouse for Canavan disease: a model for gene transfer to the central nervous system
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Background Canavan disease (CD) is an autosomal recessive leukodystrophy characterized by deยฎciency of aspartoacylase (ASPA) and increased levels of N-acetylaspartic acid (NAA) in brain and body ยฏuids, severe mental retardation and early death. Gene therapy has been attempted in a number of children