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The “motor complication syndrome” in rats with 6-OHDA lesions treated chronically with l-DOPA: Relation to dose and route of administration

✍ Scribed by Hanna S. Lindgren; Daniella Rylander; K. Elisabet Ohlin; Martin Lundblad; M. Angela Cenci

Book ID: 116284445
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 580 KB
Volume: 177
Category: Article
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2006.09.019

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## Abstract In this study, we have examined the effects of chronic L‐3,4‐dihydroxyphenylalanine (L‐DOPA) administration on the remaining dopaminergic neurons in rats with 6‐hydroxydopamine (6‐OHDA) or buffered FeCl~3~ partial lesions to the nigrostriatal tract. L‐DOPA administration increased the t