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The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia

✍ Scribed by Chapiro, E; Radford-Weiss, I; Bastard, C; Luquet, I; Lefebvre, C; Callet-Bauchu, E; Leroux, D; Talmant, P; Mozziconacci, M-J; Mugneret, F

Book ID: 109886453
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 126 KB
Volume: 22
Category: Article
ISSN: 0887-6924
DOI: 10.1038/leu.2008.102

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## Abstract The t(14;19)(q32;q13) is a recurrent chromosomal translocation reported in a variety of B‐cell leukemias and lymphomas, including chronic lymphocytic leukemia (CLL). CLL cases associated with t(14;19) often have atypical morphologic and immunophenotypic features and unmutated immunoglob