The molecule role ontology: an ontology for annotation of signal transduction pathway molecules in the scientific literature
✍ Scribed by Satoko Yamamoto; Takao Asanuma; Toshihisa Takagi; Ken Ichiro Fukuda
- Publisher
- Hindawi Publishing Corporation
- Year
- 2004
- Tongue
- English
- Weight
- 689 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1531-6912
- DOI
- 10.1002/cfg.432
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✦ Synopsis
In general, it is not easy to specify a single sequence identity for each molecule name that appears in a pathway in the scientific literature. A molecule name may stand for concepts of various granularities, from concrete objects such as H-Ras and ERK1 to abstract concepts or categories such as Ras and MAPK. Typically, the relations among molecule names derive a hierarchical structure; without a proper way to handle this knowledge, it becomes ever more difficult to develop a reliable pathway database. This paper describes an ontology that is designed to annotate molecules in the scientific literature on signal transduction pathways.