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The molecular mechanisms of Foxp3 gene regulation

โœ Scribed by Takashi Maruyama; Joanne E. Konkel; Brian F. Zamarron; WanJun Chen


Book ID
116885682
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
331 KB
Volume
23
Category
Article
ISSN
1044-5323

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## Abstract Foxp3, forkhead/winged helix transcription factor 3, is a master transcription factor for the development and function of regulatory T cells. Foxp3 has been proved to be associated with immunoregulation, autoimmune diseases, infections, and tumor immune evasion/escape. Foxp3 regulates o