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The molecular mechanism of aflatoxin B1–induced liver cancer: Is mitotic recombination involved?

✍ Scribed by Christian Sengstag


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
85 KB
Volume
19
Category
Article
ISSN
0899-1987

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Liver carcinogen aflatoxin B1 as an indu
✍ Peter Markus Stettler; Christian Sengstag 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 349 KB

## Abstract The mycotoxin aflatoxin B~1~ (AFB~1~) is one of the most potent rodent and human liver carcinogens. Upon cytochrome P450–specific metabolism, it induces mutations as well as mitotic recombination events in in vitro systems. We have found that in the lower eukaryote yeast, the recombinag