The molecular genetics of prostate cancer
β Scribed by Tapio Visakorpi
- Book ID
- 117265472
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 278 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0090-4295
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Genetically engineered mouse models have been generated to study the molecular basis of prostate cancer (PCa) development, progression, and metastasis. Selection of a prostate-specific promoter, such as the probasin (PB) and prostate specific antigen (PSA) promoters, is critical for generating suffi
The multistep nature of carcinogenesis has been repeatedly demonstrated for a variety of human cancers. Concomitant mutational activation of genes that promote cellular growth (i.e., oncogenes) and inactivation of genes that normally act to restrict or otherwise regulate growth (i.e., tumor suppress