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The molecular biology of knockdown resistance to pyrethroid insecticides

โœ Scribed by D.M. Soderlund; D.C. Knipple

Book ID
117673275
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
203 KB
Volume
33
Category
Article
ISSN
0965-1748

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Knockdown resistance (kdr) to DDT and pyrethroid insecticides maps to a sodium channel gene locus in the housefly (Musca domestica)
โœ Williamson, Martin S. ;Denholm, Ian ;Bell, Caroline A. ;Devonshire, Alan L. ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 932 KB

The voltage-sensitive sodium channel is generally regarded as the primary target site of dichloro-diphenyl-trichloro-ethane (DDT) and pyrethroid insecticides, and has been implicated in the widely reported mechanism of nerve insensitivity to these compounds. This phenomenon is expressed as knockdown