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The molecular basis of skeletal muscle weakness in a mouse model of inflammatory myopathy

✍ Scribed by Coley, William; Rayavarapu, Sree; Pandey, Gouri S.; Sabina, Richard L.; Van der Meulen, Jack H.; Ampong, Beryl; Wortmann, Robert L.; Rawat, Rashmi; Nagaraju, Kanneboyina

Book ID
118752647
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
615 KB
Volume
64
Category
Article
ISSN
0004-3591

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## Abstract ## Objective Interleukin‐1 (IL‐1) acts via its receptors to induce gene expression that mediates protein synthesis involved in inflammation. Increased expression of IL‐1Ξ± and IL‐1Ξ² in muscle tissue from patients with polymyositis and dermatomyositis has been demonstrated. It is not kno