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The molecular basis of familial hypercholesterolemia in the Netherlands


Book ID
118630758
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
154 KB
Volume
3
Category
Article
ISSN
1567-5688

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Autosomal-dominant hypercholesterolemia (ADH) has been identified as a major risk factor for coronary vascular disease (CVD) and is associated with mutations in the low-density lipoprotein receptor (LDLR) and the apolipoprotein B (APOB) gene. Since 1991 DNA samples from clinically diagnosed ADH pati