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The molecular basis of emetine resistance in chinese hamster ovary cells: Alteration in the 40S ribosomal subunit

✍ Scribed by Gupta, Radhey S.; Siminovitch, Louis

Book ID
122433155
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
588 KB
Volume
10
Category
Article
ISSN
0092-8674

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Cell lines from Chinese hamster ovary [CHO-K1-D3] and human fibroblast cells [46, XX, 18p-] were mutagenized with N-nitrosomethylurea followed by a selection for cycloheximide resistance. Two mutants resistant against the drug were selected from either wildtype. 80S ribosomes and their ribosomal sub