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The molecular architecture of the nuclear pore complex

✍ Scribed by Alber, Frank; Dokudovskaya, Svetlana; Veenhoff, Liesbeth M.; Zhang, Wenzhu; Kipper, Julia; Devos, Damien; Suprapto, Adisetyantari; Karni-Schmidt, Orit; Williams, Rosemary; Chait, Brian T.


Book ID
109897105
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
958 KB
Volume
450
Category
Article
ISSN
0028-0836

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Chromosomal DNA replication is strictly regulated through a sequence of steps that involve many macromolecular protein complexes. One of these is the GINS complex, which is required for initiation and elongation phases in eukaryotic DNA replication. The GINS complex consists of four paralogous subun