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The mode of action of 4-aminopyridine and guanidine on transmitter release from motor nerve terminals

✍ Scribed by Håkan Lundh; Stephen Thesleff

Book ID
118322432
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
162 KB
Volume
42
Category
Article
ISSN
0014-2999

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Actions of lead on transmitter release a
Actions of lead on transmitter release at mouse motor nerve terminals
✍ Yong-Xiang Wang; David M. J. Quastel 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 725 KB

The actions of lead (Pb2+) on transmitter release were studied at neuromuscular junctions in mouse diaphragm in vitro. The quantal content of end-plate potentials (EPPs) was reduced by Pb2+ in a dose-related manner consistent with inhibition of Ca2+ entry into nerve terminals, with a half-maximal ef