The Mitsunobu 1-O-esterification of 1-hydroxy-3-phenyl-1H-quinoxalin-2-one 4-oxide
โ Scribed by T. A. Kropacheva; V. K. Khlestkin
- Book ID
- 106520889
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 218 KB
- Volume
- 57
- Category
- Article
- ISSN
- 1573-9171
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The title compound, C 15 H 17 NO 2 S, synthesized as an inhibitor for 5-lipoxygenase, comprises the neutral 1,2-diethyl-3hydroxy-6-phenylthiopyridin-4(1H)-one molecule. The H atom of the hydroxy group and the carbonyl O atom form intermolecular hydrogen bonds with another molecule in a head-to-head
In the title Schiff base, C 19 H 19 N 3 O 2 , the dihydropyrazole ring is essentially planar, with an r.m.s. deviation of 0.0289 A หfor the fitted atoms. This ring makes dihedral angles of 41.8 (2) and 51.1 (3) with the phenyl and benzene rings, respectively. In the crystal structure, there is one i
were synthesized by reactions o? methyl 2-bromo-2-phmylethanorrte 1 with oFthosubstituted arylaminea 2a -2c. Subsequent reductive alkylationofthe lactams with aodium hydride and-iodobthane afforded only the N-alkylated quinoxalinone 4a and benzothiazinone 4b. Lithium aluminium hydride reduction of t