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The mitotic machinery as a source of genetic instability in cancer

โœ Scribed by German A. Pihan; Stephen J. Doxsey


Book ID
112264961
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
298 KB
Volume
9
Category
Article
ISSN
1044-579X

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## Abstract Genetic instability plays a crucial role in cancer development. The genetic stability of the cell as well as DNA methylation status could be modulated by folate levels. Several studies suggested associations between polymorphisms in folate genes and alterations in protein expression and