Accumulation of Defective Mitochondria t
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AXEL KOWALD; THOMAS B.L. KIRKWOOD
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Article
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2000
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Elsevier Science
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English
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The mitochondrial theory of ageing proposes that an accumulation of defective mitochondria is a major contributor to the cellular deterioration that underlies the ageing process. The plausibility of the mitochondrial theory depends critically upon the population dynamics of intact and mutant mitocho