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The micronucleus assay in exfoliated buccal cells: application to occupational exposure to polycyclic aromatic hydrocarbons

✍ Scribed by Bensu Karahalil; Ali Esat Karakaya; Sema Burgaz


Book ID
118626273
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
318 KB
Volume
442
Category
Article
ISSN
1383-5718

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The exfoliated cell micronucleus (MN) assay using fluorescent in situ hybridization (FISH) with a centromeric probe is a rapid method for determining the mechanism of MN formation in epithelial tissues exposed to carcinogenic agents. Here, we describe the use of this assay to detect the presence or