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The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies

โœ Scribed by Burger, Jan A.; Gribben, John G.

Book ID
121011772
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
1005 KB
Volume
24
Category
Article
ISSN
1044-579X

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The microenvironment in chronic lymphocy
The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies
โœ Burger, Jan A.; Gribben, John G. ๐Ÿ“‚ Article ๐Ÿ“… 2014 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 1005 KB

Over the last decade, the active role of the microenvironment in the pathogenesis of B cell lymphomas has been recognized, delivering signals that favor clonal expansion and drug resistance. We are only beginning to understand the complex cross talk between neoplastic B cells and the tissue microenv