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The microbial production of 3aα-H-4α- (3′-propionic acid)-5α-hydroxy-7aβ-methylhexahydro-indan-1-one-δ-lactone from cholesterol

✍ Scribed by N. P. Ferreira; P. M. Robson; J. R. Bull; W. H. Walt

Book ID: 104638352
Publisher: Springer Netherlands
Year: 1984
Tongue: English
Weight: 261 KB
Volume: 6
Category: Article
ISSN: 0141-5492
DOI: 10.1007/bf00139995

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✦ Synopsis

A mutant strain of Rhodococcus australis CSIR-236.457 which accumulates 3aa-H-4a-(3~-propionic acid) -5 s-hydroxy-7aL-methylhexahydro-lndan l-one-6-1actone from cholesterol, stiqmasterol and B-sitosteroi was studied. qhe product is produced in a 60% molar yield in a dilute black strap molasses medium containing 6-12g/~ cholesterol after a 72 hour fermentation period.

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