The MG-QOL15 for following the health-related quality of life of patients with myasthenia gravis

✍ Scribed by Ted M Burns; C.K Grouse; Gil I Wolfe; Mark R Conaway; Donald B Sanders

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 134 KB
• Volume: 43
• Category: Article
• ISSN: 0148-639X
• DOI: 10.1002/mus.21883

✦ Synopsis

Abstract

The MG‐QOL15 is helpful in informing the clinician about the patient's perception of the extent of and dissatisfaction with myasthenia gravis (MG)‐related dysfunction. The aims of this study were to determine the usefulness of the MG‐QOL15 for following individuals with MG and to guide clinical researchers who plan to use the MG‐QOL15. We assessed sensitivity and specificity for detecting clinical change and evaluated test–retest reliability. Sensitivities and specificities of various cut‐points of change in scores are presented. Also presented are means and standard deviations of MG‐QOL15 scores for all patients and for subgroups of patients. The test–retest reliability coefficient was 98.6%. The MG‐QOL15 has an acceptable longitudinal construct validity. We consider this instrument to be most useful for informing the clinician about the patient's perception and tolerance of MG‐related dysfunction. More objective measures, such as the MG Composite, should also be used to follow disease severity. Muscle Nerve, 2011