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The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations

✍ Scribed by Derval J Gaughan; Leo A.J Kluijtmans; Sandrine Barbaux; Dorothy McMaster; Ian S Young; John W.G Yarnell; Alun Evans; Alexander S Whitehead


Book ID
119434170
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
103 KB
Volume
157
Category
Article
ISSN
0021-9150

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Methionine synthase D919G polymorphism i
✍ Dawn L. Harmon; Denis C. Shields; Jayne V. Woodside; Dorothy McMaster; John W.G. πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 94 KB

Elevation in plasma homocysteine concentration has been associated with vascular disease and neural tube defects. Methionine synthase is a vitamin B(12)-dependent enzyme that catalyses the remethylation of homocysteine to methionine. Therefore, defects in this enzyme may result in elevated homocyste