The metabolism of [carboxyl-14C]aspirin in man
β Scribed by Hutt, A. J.; Caldwell, J.; Smith, R. L.
- Book ID
- 115533816
- Publisher
- Informa plc
- Year
- 1982
- Tongue
- English
- Weight
- 578 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0049-8254
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π SIMILAR VOLUMES
Following oral administration of DL-[14C]prenylamine, about 40% of the dose administered was excreted in urine within 10 days. Less than 0.1% of the dose was excreted as unchanged prenylamine. The drug was extensively metabolized to at least 20 to 25 metabolites. The structure of 12 metabolites coul
## Abstract Three healthy male subjects received single 100mg oral doses of carprofen containing 20 ΞΌCi of ^14^Cβcarprofen. Venous blood samples were drawn during the first 48 h after the dose and urine and feces were collected for 120h. Concentrations of carprofen and its metabolites in body fluid