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The metabolism of 1-aminocyclopentane-1-carboxylic acid in normal and neoplastic tissues

✍ Scribed by William R. Sterling; J.Frank Henderson; H.George Mandel; Paul K. Smith


Book ID
115768282
Publisher
Elsevier Science
Year
1962
Tongue
English
Weight
841 KB
Volume
11
Category
Article
ISSN
0006-2952

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Synthetic routes to all four diastereoisomers of 3-thymine-1-( t butoxycarbonyl)aminocyclopentane-1-carboxylic acid have been developed starting from the commercially available (S)-dimethyl malate. The key step in the synthesis involves dialkylation of N-(diphenylmethylene)glycine ethyl ester with 1