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The metabolism “in vitro” of leukotriene B4 in blood of normal subjects and asthmatic patients

✍ Scribed by J.T. Zakrzewski; A.P. Sampson; J.M. Evans; N.C. Barnes; P.J. Piper; J.F. Castello

Book ID
119050770
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
755 KB
Volume
35
Category
Article
ISSN
0090-6980

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✍ A.P. Sampson; J.M. Evans; L.G. Garland; P.J. Piper; J.F. Costello 📂 Article 📅 1990 🏛 Elsevier 🌐 English ⚖ 701 KB

The generation and metabolism of leukotrienes (LTs) B4, C4, D4, and E4 were studied in vitro in the A23187-stimulated whole blood of normal (N) and atopic asthmatic (AA) human subjects. Using a combination of reversed-phase high performance liquid chromatography and radioimmunoassay, we have demonst