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The Metabolic Substrates of Bradykinesia and Tremor in Uncomplicated Parkinson's Disease

✍ Scribed by C. Lozza; R-M. Marié; J-C. Baron


Book ID
118769954
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
225 KB
Volume
17
Category
Article
ISSN
1053-8119

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The role of the subthalamic nucleus (STN) in the origin of parkinsonian tremor is discussed. Previous studies in monkeys made parkinsonian by MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) administration suggested a direct participation of the STN in the pathophysiology of tremor. We recorded t