The Metabolic Processing of Glycosphingolipids in HT-29 Cells Is Differentiation-Dependent
✍ Scribed by J.J. Houri; A. Falbo; G. Vignali; P. Codogno; R. Ghidoni
- Book ID
- 115575058
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 443 KB
- Volume
- 202
- Category
- Article
- ISSN
- 0006-291X
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The inability of HT-29 cells to undergo an enterocytic differentiation when grown in a glucosecontaining (Glc+) medium has been recently correlated to an overall impairment of N-glycan processing. These results were obtained using confluent HT-29 cells in which the differentiation characteristics ar
## Abstract The metabolism of human low‐density lipoproteins was studied in 2 subpopulations deriving from cells of HT29, a human colon carcinoma cell line. When grown on standard medium (25 mM glucose), about 95% of these cells are undifferentiated (G^+^ cells). From this heterogeneous population,