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The metabolic activation of abacavir by human liver cytosol and expressed human alcohol dehydrogenase isozymes

✍ Scribed by John S Walsh; Melinda J Reese; Linda M Thurmond


Book ID
114008887
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
386 KB
Volume
142
Category
Article
ISSN
0009-2797

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To determine the zonal distribution of alcohol dehydrogenase in normal and cirrhotic human livers, we measured activities of this enzyme by quantitative cytochemical analysis along the liver cell plate in liver specimens from 10 normal organ donors and from 7 children with extrahepatic biliary atres