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The Merkel Cell || MOC-31, Cytokeratin 7 and S-100 Protein Immunoreactivity in Merkel Cell and Merkel Cell Carcinoma

✍ Scribed by Baumann, Klaus I.; Halata, Zdenek; Moll, Ingrid

Book ID
120306505
Publisher
Springer Berlin Heidelberg
Year
2003
Tongue
German
Weight
762 KB
Edition
2003
Category
Article
ISBN
3662103583

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✦ Synopsis

Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but their discovery has raised additional questions regarding Merkel cell function. Essential aspects of structure, development and function of normal Merkel cells and Merkel cell carcinoma are presented in short chapters, providing concise and up-to date information on this fascinating cell type.

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Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but t