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The menD and menE homologs code for 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylate synthase and O-succinylbenzoic acid–CoA synthase in the phylloquinone biosynthetic pathway of Synechocystis sp. PCC 6803

✍ Scribed by T Wade Johnson; Sushma Naithani; Charles Stewart Jr.; Boris Zybailov; A Daniel Jones; John H Golbeck; Parag R Chitnis


Book ID
117046561
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
333 KB
Volume
1557
Category
Article
ISSN
0005-2728

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Vitamin K (menaquinone) biosynthesis in
✍ Janet L. Popp; Christine Berliner; Ronald Bentley 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 640 KB

An early enzyme in menaquinone (vitamin K2) biosynthesis is the synthase forming 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) from isochorismic acid. In turn, SHCHC is aromatized to o-succinylbenzoic acid (OSB) by OSB synthase. An assay for the combined activity of these two enz