Vitamin K (menaquinone) biosynthesis in
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Janet L. Popp; Christine Berliner; Ronald Bentley
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Article
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1989
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Elsevier Science
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English
⚖ 640 KB
An early enzyme in menaquinone (vitamin K2) biosynthesis is the synthase forming 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) from isochorismic acid. In turn, SHCHC is aromatized to o-succinylbenzoic acid (OSB) by OSB synthase. An assay for the combined activity of these two enz