✦ LIBER ✦

The membrane potentials of fibroblasts in different environments

✍ Scribed by J. Bard; M. O. Wright

Publisher: John Wiley and Sons
Year: 1974
Tongue: English
Weight: 377 KB
Volume: 84
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040840116

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The membrane potentials of human embryonic lung fibroblasts have been measured in different cellular environments. Sparse cells on plastic have a mean membrane potential of −8.5 mV. As the cells progress to dense culture, the mean membrane potential rises to −14.7 mV. The mean membrane potential of fibroblasts in human embryonic lung fragments by comparison was found to be −16.5 mV. Sparse cells on collagen, at the same density as the sparse cells on plastic, have mean membrane potentials of −10.8 mV.

Sparse cells on plastic migrating from dense cellular areas, following a cut being made in a thick sheet of cells, have mean membrane potentials of −5.9 mV.

The significance of these results in relation to cellular environments has been discussed.

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