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The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL-6 and the IL-6 receptor

✍ Scribed by Ursula Horsten; Hildegard Schmitz-Van de Leur; Jürgen Müllberg; Peter C. Heinrich; Stefan Rose-John

Book ID
115930458
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
556 KB
Volume
360
Category
Article
ISSN
0014-5793

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## Abstract Leukemia inhibitory factor (LIF) and its receptor (LIFR) are “twins” of Oncostatin M (OSM) and OSMR, respectively, likely having arisen through gene duplications. We compared their effects in a bone nodule‐forming model of in vitro osteogenesis, rat calvaria (RC) cell cultures. Using a