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The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers

✍ Scribed by Nicolas Jonckheere; Isabelle Van Seuningen

Book ID: 116309141
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 516 KB
Volume: 92
Category: Article
ISSN: 0300-9084
DOI: 10.1016/j.biochi.2009.09.018

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## Abstract DAPK1, a ca^+2^/calmodulin regulated serine/threonine kinase, is a major tumor suppressor, whose expression is lost in multiple tumor types. However, the mechanisms contributing to it are unclear. We have recently shown that CCAAT/Enhancer binding protein‐β (C/EBP‐β) is required for the