The meisenheimer transformation of (+)-nupharidine

✍ Scribed by R.T. Lalonde; J.T. Woolever; E. Auer; C.F. Wong

• Book ID: 104236650
• Publisher: Elsevier Science
• Year: 1972
• Tongue: French
• Weight: 142 KB
• Volume: 13
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)84668-2

✦ Synopsis

According to a modified procedure (2) for effecting Meisenheimer rearrangements (3), (+)-nupharidine, ,1, was heated in refluxing dimethylacetamide for 1.5 hours to obtain, in 65% yield, the liquid, fused-ring, hexahydro-1,2-oxasepine, 4