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The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

✍ Scribed by Kumar L Hari; Anne Santerre; Jeff J Sekelsky; Kim S McKim; James B Boyd; R Scott Hawley


Book ID
116088711
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
825 KB
Volume
82
Category
Article
ISSN
0092-8674

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Expression of the ATDC (ataxia telangiec
✍ Keith R. Laderoute; A. Merrill Knapp; Christopher J. Green; Robert M. Sutherland πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 922 KB

The ATDC gene was originally identified by its ability to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. Because hypersensitivity to ionizing radiation is an important feature of the AT phenotype, we reasoned that ATDC may function generally in the supp