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The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA (‘ecstasy’)-induced degeneration of 5-HT nerve endings in rat brain

✍ Scribed by V Sanchez; J Camarero; B Esteban; M J Peter; A R Green; M I Colado


Book ID
110005843
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
296 KB
Volume
134
Category
Article
ISSN
0007-1188

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Long-lasting neuroprotective effect of s
✍ Elena Puerta; Lucia Barros-Miñones; Isabel Hervias; Violeta Gomez-Rodriguez; Lou 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 718 KB

## Abstract Sildenafil, given shortly before 3,4‐methylenedioxymethamphetamine (MDMA), affords protection against 5‐hydroxytryptamine (5‐HT) depletions caused by this amphetamine derivative by an acute preconditioning‐like mechanism. Because acute and delayed preconditionings do not share the same