The mechanism of the reaction of hydroxylamine and O-methylhydroxylamine with cytidine

✍ Scribed by N.K. Kochetkov; E.I. Budowsky; E.D. Sverdlov; R.P. Shibaeva; V.N. Shibaev; G.S. Monastirskaya

• Publisher: Elsevier Science
• Year: 1967
• Tongue: French
• Weight: 215 KB
• Volume: 8
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)89864-6

✦ Synopsis

The mutagenic action of hydroxylomine (HA) and O-methylhydroxylomine (OMHA) appears moinly to be due to their reactions with cytosine residues in nucleic acids (l-6). The mechanism of these interactions is not fully understood; the interpretations of the genetic data from the chemical point of view are rather controdictious (7-9).