✦ LIBER ✦

The mechanism of the phosphoryl transfer catalyzed by Yersinia protein-tyrosine phosphatase: a computational and isotope effect study

✍ Scribed by Przemyslaw G Czyryca; Alvan C Hengge

Book ID: 114149012
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 800 KB
Volume: 1547
Category: Article
ISSN: 0167-4838
DOI: 10.1016/s0167-4838(01)00191-1

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Computational Study of the Phosphoryl Tr

Computational Study of the Phosphoryl Transfer Catalyzed by a Cyclin-Dependent Kinase

✍ Marco De Vivo; Andrea Cavalli; Paolo Carloni; Maurizio Recanatini 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 616 KB

## Abstract A cyclin‐dependent kinase, Cdk2, catalyzes the transfer of the γ‐phosphate from ATP to a threonine or serine residue of its polypeptide substrates. Here, we investigate aspects of the reaction mechanism of Cdk2 by gas‐phase density functional calculations, classical molecular dynamics,

Does Positive Charge at the Active Sites

Does Positive Charge at the Active Sites of Phosphatases Cause a Change in Mechanism? The Effect of the Conserved Arginine on the Transition State for Phosphoryl Transfer in the Protein-Tyrosine Phosphatase from Yersinia

✍ Hoff, Richard H.; Wu, Li; Zhou, Bo; Zhang, Zhong-Yin; Hengge, Alvan C. 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 156 KB

Stabilization of Charges and Protonation

Stabilization of Charges and Protonation States in the Active Site of the Protein Tyrosine Phosphatases: A Computational Study †

✍ Dillet, Valérie; Van Etten, Robert L.; Bashford, Donald 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 212 KB

A Computational Study of the Olefin Epox

A Computational Study of the Olefin Epoxidation Mechanism Catalyzed by Cyclopentadienyloxidomolybdenum(VI) Complexes

✍ Aleix Comas-Vives; Agustí Lledós; Rinaldo Poli 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 675 KB

Activation of protein phosphatase 2A by

Activation of protein phosphatase 2A by cAMP-dependent protein kinase-catalyzed phosphorylation of the 74-kDa B″ (δ) regulatory subunit in vitro and identification of the phosphorylation sites

✍ Hirofumi Usui; Rintaro Inoue; Osamu Tanabe; Yasumasa Nishito; Masahiro Shimizu; 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 138 KB

Studies on the mechanism of rapid activa

Studies on the mechanism of rapid activation of protein tyrosine phosphorylation activities, particularly c-Src kinase, by TCDD in MCF10A

✍ Olga Mazina; Sujin Park; Hiromi Sano; Patrick Wong; Fumio Matsumura 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB 👁 2 views

While the process of the Ah receptor activation leading to cytochrome P450 induction has been well studied, the mechanism and the process through which the Ah receptor activates tyrosine kinases, within a few minutes of its ligand binding, is not known. Previously, it was reported by Tannheimer et a