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The mechanism of platelet adherence to sinusoidal endothelial cells (SEC) after cold preservation

✍ Scribed by Upadhya, Gundumi A.; Strasberg, Steven M.

Book ID
123383586
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
204 KB
Volume
118
Category
Article
ISSN
0016-5085

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✍ Stefan A. Topp; Gundumi A. Upadhya; Steven M. Strasberg πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 376 KB

Cold preservation of rat sinusoidal endothelial cells causes actin disassembly, cell rounding, matrix metalloproteinase (MMP) secretion, and platelet adhesiveness. Studies in rats suggest that gelatinases MMP2 and MMP9 are the key mediators of the injury. We created a model of cold preservation inju