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The mechanism of lipid-binding by plasma lipoproteins

✍ Scribed by Richard L. Jackson; Joel D. Morrisett; Antonio M. Gotto; Jere P. Segrest


Publisher
Springer
Year
1975
Tongue
English
Weight
759 KB
Volume
6
Category
Article
ISSN
0300-8177

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The alteration of plasma lipoproteins by
✍ Kathryn Woodburn; David Kessel πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 English βš– 889 KB

Cremophor EL (CRM) is a non-ionic amphipathic emulsifier which has been used as a parenteral vehicle for many hydrophobic drugs. At concentrations above 0.4 mg ml-1, CRM alters lipoproteins so as to reduce their electrophoretic mobility; high density lipoprotein (HDL) is somewhat more sensitive than