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The mechanism of inhibition of endothelin-1-induced stimulation of DNA synthesis in rat articular chondrocytes

✍ Scribed by A.-M Khatib; D Ribault; M Quintero; A Barbara; J Fiet; D.R Mitrovic

Book ID
117463759
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
292 KB
Volume
132
Category
Article
ISSN
0303-7207

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✍ Geoffrey Krystal; Gregory M. Morris; Leon Sokoloff πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 754 KB

## Abstract The addition of 0.2 m__M__ Na L‐ascorbate increased the incorporation of ^3^H‐thymidine by rabbit articular chondrocytes in cell and organ culture. The stimulatory response of explants to ascorbate was potentiated by pretreatment of the cartilage with 0.2% clostridial collagenase (type