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The mechanism of improved sodium homeostasis of low-dose losartan in pre-ascitic cirrhosis

✍ Scribed by Florence Wong; Peter Liu; Laurence Blendis


Book ID
118565138
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
112 KB
Volume
36
Category
Article
ISSN
0168-8278

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Post-TIPS ascites-free patients with cirrhosis and previous refractory ascites demonstrate subtle sodium retention when challenged with a high sodium load. This is also observed in pre-ascitic patients with cirrhosis. This phenomenon is dependent on an intrarenal angiotensin II (ANG II) mechanism re