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The mechanism of Hsp70 chaperones: (entropic) pulling the models together

โœ Scribed by Pierre Goloubinoff; Paolo De Los Rios


Book ID
113931379
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
909 KB
Volume
32
Category
Article
ISSN
0968-0004

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## Abstract Activation of the Hsp90 chaperone system is a characteristic of cancer cells. The regulation of chaperone activities involves their interaction with cochaperones; therefore we investigated the expression of Hsp70 and Hsp90 and their specific co-chaperones HOP and CHIP in cancer cell lin