The mechanism of anaphase spindle elongation
β Scribed by W. Z. Cande; C. J. Hogan
- Book ID
- 102761594
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 716 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
β¦ Synopsis
A t anaphase chromosomes move to the spindle poles (anaphase A ) and the spindle poles move apart (anaphase B).
In vitro studies using isolated diatom spindles demonstrate that the primary mechanochemical event responsible for spindle elongation is the sliding apart of havspindle microtubules. Further, these forces are generated within the zone of microtubule overlap in the spindle midzone.
π SIMILAR VOLUMES
DSK1 is a kinesin-related protein that is involved in anaphase spindle elongation in the diatom Cylindrotheca fuisiformis [Wein et al., 1996: J. Cell Biol. 113:595-604]. DSK1 staining appeared to be concentrated in the gap that forms as the two half-spindles separate, suggesting that DSK1 may be par