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The mechanism of action of the tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in the control of haematopoietic stem cell proliferation

✍ Scribed by S. Robinson; M. Lenfant; J. Wdzieczak-Bakala; J. Melville; A. Riches


Book ID
114715954
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
680 KB
Volume
25
Category
Article
ISSN
0960-7722

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## Abstract The tetrapeptide __N__‐Acetyl‐Ser‐Asp‐Lys‐Pro (AcSDKP), an inhibitor of haematopoietic stem cell proliferation, reduces __in vivo__ and __in vitro__ the damage to the stem cell compartment resulting from treatment with chemotherapeutic agents or ionizing radiations. In order to provide