The measurement of 13,14-dihydro-15-keto
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R. W. Kelly; M. H. Abel
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Article
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1983
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John Wiley and Sons
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English
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The main metabolite of prostaglandin E, (PGE2) 13,14-dihydro-Sketo-PGE, readily dehydrates and can subsequently form a cyclic derivative. This problem can be overcome by the immediate formation of oximes of the 9 and 15 ketones in aqueous solution followed by subsequent extraction, methylation and t