Tirapazamine is a hypoxic cell cytotoxin in phase II/III trials. To further understand its mechanism of action in vivo, we examined the effect of tirapazamine on tumor energy metabolism and pH. RIF-1 and SCCVII tumors were grown subcutaneously in the flanks of C3H mice. Tumor energy metabolism, expr
The measurement of radiosensitizer-induced changes in mouse tumor metabolism by 31P magnetic resonance spectroscopy
β Scribed by Pauline J. Wood; Christopher J.R. Counsell; Jane C.M. Bremner; Michael R. Horsman; Gerald E. Adams
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 394 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0360-3016
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