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The mean frequency of transcriptional bursting and its variation in single cells

✍ Scribed by Moxun Tang

Publisher
Springer
Year
2009
Tongue
English
Weight
597 KB
Volume
60
Category
Article
ISSN
0303-6812

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## Abstract The synthetic protease inhibitor N‐tosyl‐L‐lysine‐chloromethyl ketone (TLCK) acts to inhibit transcription when added to cell lines growing in vitro. This inhibition of transcription is most pronounced in transformed cells where TLCK is very toxic at concentrations as low as 25 ΞΌg/ml of