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The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases

✍ Scribed by Andrew J.P. Docherty; James O'Connell; Tom Crabbe; Sarojani Angal; Gillian Murphy

Book ID
113271830
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
906 KB
Volume
10
Category
Article
ISSN
0167-7799

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Background: Recurrence of disease after surgically induced remission constitutes a major and largely unpredictable problem in Crohn's disease (CD). Matrix metalloproteinases (MMP) and the tissue inhibitors of metalloproteinases (TIMP) are involved in the (etio)pathogenesis of CD and may thereby also