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The mass spectrometer as a chlorine-selective chromatographic detector : II. Applications to chemical systems

✍ Scribed by J.L. LaBrosse; R.J. Anderegg

Book ID: 104146660
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 698 KB
Volume: 314
Category: Article
ISSN: 1873-3778
DOI: 10.1016/s0021-9673(01)97725-8

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✦ Synopsis

A chlorine-selective chromatographic detector based on the computer analysis of gas chromatographic-mass spectrometric data was described in the previous paper. The presence of chlorine is inferred from isotope cluster patterns in the mass spectra; the computer is instructed to locate these patterns and indicate which spectra are most likely to arise from chlorinated compounds. The application of this detector to a drug metabolism study and the analysis of chlorinated species in an environmental matrix are presented. The performance of the detector in these systems is quite good, even for compounds of low abundance in a mixture.

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