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The many roles of RANKL-RANK signaling in bone, breast and cancer

✍ Scribed by Schramek, Daniel; Penninger, Josef M

Book ID
118069980
Publisher
Nature Publishing Group
Year
2011
Weight
466 KB
Volume
8
Category
Article
ISSN
1940-8692

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Genetic variation in the RANKL/RANK/OPG
Genetic variation in the RANKL/RANK/OPG signaling pathway is associated with bone turnover and bone mineral density in men
✍ Delnaz Roshandel; Kate L Holliday; Stephen R Pye; Steven Boonen; Herman Borghs; πŸ“‚ Article πŸ“… 2010 πŸ› American Society for Bone and Mineral Research 🌐 English βš– 220 KB πŸ‘ 1 views

## Abstract The aim of this study was to determine if single‐nucleotide polymorphisms (SNPs) in __RANKL__, __RANK__, and __OPG__ influence bone turnover and bone mineral density (BMD) in men. Pairwise tag SNPs (__r__^2^ β‰₯ 0.8) were selected for __RANKL__, __RANK__, and __OPG__ and their 10‐kb flank